Centre for Advanced Medical Products (CAMP). It is a Vinnova-funded project that focuses on the science and technology required to translate ATMPs from the lab to the clinic, including the development of bioprocesses, GMP production and logistics. CAMP drives collaboration between researchers, GMP-competent resources, industry and hospitals.
CAMP will receive SEK 48 million between 2018 and 2023. This is part of the Swedish government’s commitment of SEK 320 million to make Sweden a world leader in advanced biologics.
Overall organizational goals
- Build a strong public-private partnership with governments, academia, healthcare, patient organisations and industry to accelerate new breakthrough ATMP therapies for patients.
- Create strong research and development activities in Sweden to attract global interest and investment in the ATMP field.
- Providing a national infrastructure to pave the way for the commercialisation of ATMPs for the benefit of patients and society.
- The overall long-term goal is to develop general principles and methods for cell process development for an efficient transfer from preclinical to clinical, GMP-compliant production.
The research objectives are to develop solutions to:
- Reduce production errors due to starting materials
- Increase efficiency and quality assurance at different stages of the production process for different ATMPs.
- Minimize errors due to infection and immunogenic residues
These objectives shall be achieved through the following tasks:
- Development of a comprehensive analysis algorithm to predict production errors related to starting materials.
- Establishment of label-free sorting for enrichment of cell preparations with high potential for clinical use.
- Development of large-scale manufacturing processes for cellular ATMPs.
- Recellularisation of tissues and organs for next-generation transplantation.
- Development of quality control and sterilization techniques for tissue engineering.
- Process development for efficient transfer from laboratory bench to GMP manufacturing
